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Estradiol Delivery Methods

Published Sunday, May 28, 2023

DRAFT

A comparison of the various ways I've taken estradiol since starting HRT.

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I thought it might be useful to write out my experiences with the four methods of taking estradiol I’ve tried.

  • patches
    • wouldn’t consistently stay on me
    • could feel the effects wearing off 3-4 days after application
    • insurance sucks
  • sublingual pills
    • worked alright, except:
    • could feel them wearing off ~5-6 hours after taking a dose
    • apparently hard to measure levels? had one test at ~200 mg/ml and another at 400+ mg/ml at same dosage
  • swallowed pills
    • could not get ideal levels with a reasonable number of pills, but:
    • couldn’t actually feel them wearing off even at 12 hours between doses
  • injections
    • holy shit these are great
    • was kinda nervous the first few times I injected myself, but I got used to it
    • cannot feel it wearing off between doses
    • levels are actually good??
    • insurance sucks pt. 2

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